Benzocaine hydrochloride: Synonyms: Ethyl 4-aminobenzoate hydrochloride: Molecular Structure: Molecular Formula: C 9 H 11 NO 2. Benzydamine (also known as Tantum Verde and branded in some countries as Difflam and Septabene), available as the hydrochloride salt, is a locally acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties for pain relief and anti-inflammatory treatment of inflammatory conditions of the mouth and throat. Pennsauken, NJ; 2006 Sept. D'Ans-Lax, Taschenbuch für Chemiker und Physiker, 4. Benzocaine topical should not be used to treat teething pain in infants, and is not approved for use in a child younger than 2 years old. Use the smallest amount needed to numb the skin or relieve pain. Lexicomp Online, Adult and Pediatric Lexi-Drugs Online, Hudson, Ohio: Lexi-Comp, Inc.; 2013; April 15, 2013. Stop using benzocaine topical and call your doctor at once if you have: severe burning, stinging, or sensitivity where the medicine is applied; oozing, blistering, or any signs of infection. In: PDR Physicians" desk reference. I know that benzocaine is: C9H11NO2 ... but how do I come up with the product? This is a potentially fatal condition called methemoglobinemia (met-HEEM-oh glo-bin-EE-mee-a). Orajel Maximum Strength (Del). Do not spray this medication onto your face. Washington, DC: American Pharmaceutical Association, 1993: 817, 818, 826. 1993. We comply with the HONcode standard for trustworthy health information -, Sympathomimetic Agents—Cardiovascular Use (Parenteral-Systemic). Benzocaine behoort tot de groep van de zogenaamde para substanties.

Geburtstag: Eduard Ritsert und das Anaesthesin", "Pain perception and anaesthesia in research frogs", "Amphibian Anesthesia — Research at Penn State", 4-Aminopyridine (fampridine/dalfampridine), Transient receptor potential channel modulators,, Articles with dead external links from September 2020, Articles with failed verification from September 2020, Short description is different from Wikidata, Drugboxes which contain changes to watched fields, Articles with unsourced statements from September 2020, Creative Commons Attribution-ShareAlike License, Local anesthesia of oral and pharyngeal mucous membranes (sore throat, cold sores, mouth ulcers, toothache, sore gums, denture irritation), Some glycerol-based ear medications for use in removing excess wax as well as relieving ear conditions such as. Beilstein/REAXYS Number: 638434 .

Diagnosis and treatment of human poisoning. Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, ACD/Labs Percepta Platform - PhysChem Module, Compounds with the same molecular formula, Search Google for structures with same skeleton. 28th ed. Select one or more newsletters to continue. [26] The density of benzocaine is 1.17 g/cm3. mild stinging, burning, or itching where the medicine is applied; dry white flakes where the medicine was applied. Montvale, NJ: Medical Economics Data Production Co, 1993: 559. Benzocaine, Butamben, and Tetracaine Hydrochloride Drug Information from Benzocaine topical is used to reduce pain or discomfort caused by minor skin irritations, sore throat, sunburn, vaginal or rectal irritation, ingrown toenails, hemorrhoids, and many other sources of minor pain on a surface of the body.


Avoid using the medicine on skin that is raw or blistered, such as a severe burn or abrasion. Since benzocaine topical is used when needed, you may not be on a dosing schedule.

Benzocaine acts to inhibit the voltage-dependent sodium channels (VDSCs) on the neuron membrane, stopping the propagation of the action potential.

If you apply benzocaine topical to your chest, avoid areas that may come into contact with the baby's mouth. Ottawa: Canadian Pharmaceutical Association, 1993: 1375-6. Do not take a rectal suppository by mouth. Do not use benzocaine topical if you have ever had methemoglobinemia. If using the spray, hold the container 6 to 12 inches away from the skin. Benzocaine topical should not be used to treat teething pain in infants, and is not approved for use in a child younger than 2 years old. Panel comments, Lidocaine and Prilocaine (Topical) monograph draft 6/93. Remove the wrapper, but avoid handling the suppository too long or it will melt. There are many brands and forms of benzocaine topical available. Benzoic acid, 4-ami no-, ethyl ester, h ydrochloride. 28th ed.

[36][37], A bath solution of benzocaine has been used to anesthetize amphibians for surgery. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Americaine Anesthetic Lubricant (Fisons), Rev 6/92. No predicted properties have been calculated for this compound. Xylocaine 4% Topical Solution (Astra). Medical toxicology. System Maintenance Alert: Due to planned maintenance of our internal systems, web functionality including order placement, price and availability checks and SDS display will not be available for Asia and several European countries from Saturday, November 7th at 2:30 CET until Sunday, November 8th at 7:00 AM CET.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

In: PDR Physicians' desk reference. Not all brands are listed on this leaflet. Still have questions?

Montvale, NJ: Medical Economics Data Production Co, 1993: 558-9. USAN 1994. Cetacaine (benzocaine 14%, tetracaine 2% and butamben 2%) spray, gel and liquid prescribing information. Why can a secondary carbocation be more stable than a tertiary. Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA). Medical use. In Poland it is included, together with menthol and zinc oxide, in the liquid powder (not to be confused with the liquid, Cream (ex. The formula for the conjugate acid of HC2O4- is? Laat ons weten wat u vindt van dit arikel. Benzocaine is a local anesthetic (numbing medication). You may report side effects to FDA at 1-800-FDA-1088. 4th ed Volume 2. Signs and symptoms may occur within minutes or up to 2 hours after using benzocaine topical in the mouth or throat. In the US, products containing benzocaine for oral application are contraindicated in children younger than two years old.

Xylocaine 10% Oral Aerosol product monograph (Astra—Canada), Rev 12/93, Rec 1/94. [27] Whilst giving a numbing effect similar to cocaine, users prefer Benzocaine as it is a better bulking and binding agent that can't be detected once mixed. Articles of Benzocaine hydrochloride are included as well. CopyCopied, InChI=1S/C9H11NO2.ClH/c1-2-12-9(11)7-3-5-8(10)6-4-7;/h3-6H,2,10H2,1H3;1H Generic Name: benzocaine topical (BENZ oh kane TOP ik al)Brand Name: Americaine, Anacaine, Anbesol Gel, Benzodent, Cepacol Ultra, Dent-O-Kain, Dermoplast, Kank-a, Lanacane, Medicone Maximum Strength, Numzident, Num-Zit, Orabase, Orajel, Outgro Pain Relief, Retre-Gel, Solarcaine Aerosol, Topex, zilactin-B, all 100 brand namesAmericaine Anesthetic Lubricant, Chiggerex, Spec-T, Maintain, Orabase Lip Healer, Orajel Mouth-Aid, Orajel Maximum Strength, Orajel Baby, Orajel Denture, Detane, Foille Plus, Hurricaine, Isodettes, Lanacane with Aloe, Anbesol Maximum Strength, Orajel D, Orajel Baby Nighttime, Mosco Nail A Cain, Orabase Baby Teething Gel, Orabase with Benzocaine, Anbesol Baby Teeth, Vagisil Feminine Cream, Bicozene, Solarcaine Plus Aloe (obsolete), Sting-Kill, Americaine Hemorrhoidal, Hem-Prep, Babee Teething Lotion, Rid-A-Pain, Orajel Maximum Strength PM, Chigger-Tox, Chloraseptic (obsolete), Orajel Mouth Aid, Anbesol Cold Sore Therapy, Skeeter Stik, Anbesol Extra Strength, Topex Topical Anethetic, Hurricaine Kit, Cepacol Regular Strength, Cepacol Maximun Strength(obsolete), Cepacol Extra Strength Cherry, Cepacol Extra Strength Menthol Sugar Free, Cepacol Extra Strength Cherry Sugar Free, Dermoplast Antibacterial (obsolete), Cepacol Maximum Strength Mint, Cepacol Maximum Strength Honey Lemon, Cepacol Extra Strength Citrus, Zilactin Toothache, Orajel Medicated Mouth Sores, Anbesol Liquid, Boil Ease Pain Relieving, Orajel Denture Plus, Anbesol Baby, Cepacol Maximum Strength Menthol, Anbesol Liquid Cool Mint, Baby Orajel Nighttime Formula, Benz-O-Sthetic, Zilactin Toothache and Gum Pain Reliever, Play Longer, Orajel Regular Strength, Caine Tips Oral Pain Relief, Benzo-O-Sthetic, Cepacol Extra Strength, Hurricaine Snap-n-Go, Orabase Gel-B, Orajel Severe Pain Formula, Lanacane Maximum Strength, Benz-Protect (obsolete), Orajel Mouth Sore Medicine, Cepacol Extra Strength Menthol, Cepacol Extra Strength Honey Lemon, Cepacol Dual Relief Sore Throat Cherry, Cepacol Dual Relief Sore Throat Mint, OraMagic Plus, Trocaine, Oral Pain Relief, Cepacol Fizzlers, Cepacol Sore Throat & Coating, Cepacol Sensations Warming, Cepacol Sensations Hydra, LolliCaine, Medically reviewed by on May 29, 2020 – Written by Cerner Multum. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. 1993.

In: Krogh CME, editor. Use the smallest amount needed. In: Krogh CME, editor. Montvale, NJ: Medical Economics Data, 1993: 90, 128, 197, 250, 407, 416, 450, 487, 521, 573, 576. Ritsert, E. (1925) "Über den Werdegang des Anästhesins" (On the development of Anästhesin), "Safety Alerts for Human Medical Products - Oral Over-the-Counter Benzocaine Products: Drug Safety Communication - Risk of Serious and Potentially Fatal Blood Disorder", "Ultra Chloraseptic Anaesthetic Throat Spray 0.71% - Summary of Product Characteristics (SmPC) - (eMC)", "Orajel - Oral Care for the Whole Family", "Colgate Orabase Paste with Benzocaine | Indications | Dental Products", "Benzocaine Topical Products: Sprays, Gels and Liquids – Risk of Methemoglobinemia", "FDA Drug Safety Communication: Reports of a rare, but serious and potentially fatal adverse effect with the use of over-the-counter (OTC) benzocaine gels and liquids applied to the gums or mouth", "Allergic contact dermatitis to benzocaine: The importance of concomitant positive patch test results", "Go easy on medicated lotions, creams, gels", "Monographs: Pharmaceutical substances: Benzocainum – Benzocaine", "Drug prices: All cut up : Cocaine is cheaper, but weaker", "Ueber Esterbildung bei aromatischen Amidosäuren", "Ueber das durch Einwirkung von Jodwasserstoff auf Mannit beziehungsweise auf Melampyrin (Dulcit) entstehende β Hexyljodür und einige seiner Derivate", "Ueber die Verbindungen aus Benzoylchlorid oder Phtalylchlorid und den Estern der drei Oxybenzoësäuren", "150.

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